Overview

Globally, STIs are of major concern in the realm of public health, and particular attention should be paid to syphilis. Early diagnosis and treatment of syphilis are extremely important to improve public health levels. With that being said, there are various available options for confirming/monitoring syphilis infection; one method that is used quite frequently is known as the TPHA test (Titre Test for Human Immunoglobulin A). Prices for the TPHA test can vary between INR 1,200 to INR 1,700 depending on location.

This article provides you with everything you need to know about the TPHA test: its purpose, procedure, test result interpretation, reasons City Imaging & Clinical Labs can be trusted for accurate testing.

What is the TPHA Titre Test?

The TPHA (Hem-agglutination Assay against Treponema Pallidum) is a blood test that detects antibodies to Treponema Pallidum, the bacterium that causes syphilis.

Other Names of TPHA Test:

• TPHA Test
• Treponema Pallidum Antibody Test
• Syphilis Confirmatory Test

What is “Titre” in TPHA?

The term “titre” (or titre) refers to the concentration of antibodies in the blood by measuring with diluted blood samples.

For example:

• 1:80
• 1:160
• 1:320

Higher titres generally indicate:

• Active infection
• Past infection

Why is the TPHA Titre Test Done?

The TPHA titre test is performed for several important reasons:

1. Syphilis Infection
2. Analyse Disease History

Determine whether the infection is:

• Recent
• Past
• Treated

1. Supporting Clinical Diagnosis

Used along with symptoms such as:

• Genital sores
• Skin rashes
• Fever and fatigue

1. Prenatal Screening

How Does the TPHA Test Work?

1. Sample Collection: A blood sample is taken by the professional technician from the patient.
2. Antigen Exposure: The blood sample is carefully mixed with red blood cells in which Treponema Pallidum antigens are present.
3. Reaction Observation
   • If antibodies are present → clumping (positive result)
   • If absent → no clumping (negative result)
4. Titre Measurement: Serial dilutions are performed to determine antibody concentration.

How to understand the results of TPHA Titre Test?

What are the important points about TPHA results?

• TPHA remains positive for life
• Cannot distinguish between active and past infection alone
• Must be interpreted along with:
  • VDRL/RPR test
  • Clinical symptoms
  • Patient history

What is the difference between TPHA and VDRL test?

Who Should Take the TPHA Titre Test?

The test is recommended for:

• Individuals with positive VDRL/RPR results
• Symptoms of syphilis
• Pregnant women
• Multiple sexual partners
• Patients with HIV or other STIs
• Blood donors

What are the symptoms of Syphilis?

Primary Stage:

• Painless sores
• Swollen lymph nodes

Secondary Stage:

• Skin rash
• Fever
• Sore throat
• Fatigue

Latent Stage:

• No visible symptoms

Tertiary Stage:

• Organ damage
• Neurological complications

What are the advantages of the TPHA Titre test?

1. High Accuracy
2. Reliable Confirmation
3. Simple Procedure
4. Useful in Late Stages

What are the limitations of the TPHA Test?

1. Cannot differentiate Active vs Past Infection
2. Lifelong Positivity
3. Not Useful for Monitoring Treatment

What are the preparations for the TPHA test?

Before the Test:

• No fasting needed
• Inform your doctor about medications
• Share medical and sexual history

What is the procedure of TPHA titre at City Imaging?

1. Registration and consultation
2. Blood sample collection
3. Laboratory analysis
4. Report generation

Time Required:

• Sample collection: 5 to 10 minutes
• Report delivery: Usually within 24 to 48 hours

What is the importance of early detection?

Untreated syphilis can lead to serious complications, including:

• Heart disease
• Brain damage
• Infertility
• Pregnancy complications

Why Choose City Imaging for TPHA Testing?

Our Key Features:

• Advanced diagnostic technology
• Experienced lab professionals
• Strict quality control standards
• Quick and reliable reports
• Affordable pricing
• Confidential testing

What is the price of the TPHA titre test in Delhi?

The TPHA titre test can be performed in Delhi at the price ranges from INR 1,200 to INR 1,700. The price may vary slightly depending on the machine used, location and type of test.

How to book TPHA titre test online at City Imaging?

Patients can book the TPHA titre test online at City Imaging by visiting the website and booking the appointment online. Patients can also dial numbers and they will guide you for booking a test. City Imaging also provides home sample collection features through which professionals take samples of patients from their home and they don’t have to visit diagnostic centre.

Which TPHA titre test centre is near me in Delhi?

The TPHA titre test centre near me in Delhi is City Imaging which has a patient friendly environment, skilled radiology specialists, accurate and fast reports, modern equipment and convenient location. They provide test at reasonable rates without compromising the quality of tests. This diagnostic centre is licensed and has long experience in diagnostic fields.

Frequently Asked Questions (FAQs)

Is hospitalisation required?

No, you can go home the same day after testing as it is similar to other blood tests.

How long does TPHA remain positive?

It may remain positive for life.

Is TPHA titre test compulsory during pregnancy?

It is not an essential test but a doctor may recommend this test if symptoms may appear.

Is the TPHA titre test painful?

No, it involves a routine conventional blood collection from a vein which may cause little discomfort.

Do I need to fast for the TPHA titre test?

No fasting is not needed for doing TPHA titre test but you must also take consent from the doctor.

Can TPHA detect early syphilis?

It may not detect very early infection. Other tests are used first for detection.

What to do if my TPHA titre test reports come negative?

There is no need to worry but you must take great care and do regular checkups if symptoms appear again.

Is the test safe if done during pregnancy?

Yes, it is completely safe. It is the same routine blood test where a blood sample is taken from the vein of the arm.

Can I book an online TPHA titre test in Delhi?

Yes, you can book an online TPHA titre test in Delhi from City Imaging very comfortably.

Can TPHA titre test be done anytime during pregnancy?

Yes, it can be done in any month of pregnancy but doctors recommend it in early pregnancy.

What if the TPHA titre test is positive?

It usually indicates the strong infection caused by bacteria known as Treponema Pallidum.

Which lab gives test reports with accurate results in Delhi?

City Imaging has a track record in giving reports with high accuracy because it has advanced medical equipment and experienced professionals.

Is the TPHA test done prior to pregnancy?

Yes, doctors advised to do TPHA titre test to confirm immunity of pregnant women and aids to avoid pregnancy complications.

How soon will I get my results?

Most reports in many labs are available within 24 hours but it also depends on your slot.