QUADRUPLE MARKER***

3200

Additional information
DepartmentIMMUNOLOGY
Speciality NameQUADRUPLE MARKER***
Test typePathology
Report24 Hours
Also known as
AvailabilityAll centre

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Preparation

Valid between 14-22 weeks gestation (Ideal 15-20 weeks).

Overview

While on their amazing way through the journey of pregnancy, many expecting parents are anxious to know that their baby is healthy. One of the best ways to gain that knowledge includes having a Quadruple Marker Test completed in the second trimester. This allows mothers to make sound decisions regarding their pregnancy.  This test gives accurate results, cost effective test and is effective in determining any risk for the unborn baby.

What is the Quadruple Marker Test?

The 4th Trimester Test or Quad Screen Test is 2 names for the same lab test. The Quadruple Marker Test checks for potential fetal birth defects and/or congenital abnormalities in your baby's growth from week 15 through week 20. The proper time to have this blood test is between 16 and 18 weeks into your pregnancy.

This test measures four important substances in the mother’s blood:

  1. Alpha-Fetoprotein
  2. Human Chorionic Gonadotropin
  3. Unconjugated Estriol
  4. Inhibin A

Doctors determine the levels of the four markers with gestational age and then calculate the danger of certain birth defects and chromosomal abnormalities.

Why is the Quadruple Marker Test Done?

Quadruple test is done to determine the risk of:

  • Down Syndrome
  • Edward Syndrome
  • Neural Tube Defects
  • Wall defects

How to understand the Four Markers?

S. No.MarkerRole in PregnancyWhat Abnormal Levels May Suggest
1AFPProduced by fetal liverNeural tube defects, down syndrome
2hCGProduced by placentaHigh levels: Down syndrome
3uE3Produced by fetus & placentaLow levels: Chromosomal abnormalities
4Inhibin AProduced by placentaHigh levels: Down syndrome

 

Who Should Take the Quadruple Marker Test?

Doctors usually recommend this test to:

  • Pregnant women
  • Women above 35 years of age
  • Who missed first trimester screening
  • Women with family history of genetic disorders
  • Mothers with abnormal ultrasound findings
  • Previous pregnancy complications

What is the procedure of the Quadruple Marker Test?

The quadruple marker test procedure is simple, quick and safe.

The steps involved in doing this test are:

  1. Doctor’s Advice: Gynaecologist suggests this test during the second trimester.
  2. Blood Sample Collection: A blood sample is drawn from a vein in the arm and collected in test tube.
  3. Laboratory Testing: The four markers are determined by the doctor carefully.
  4. Risk Calculation: Software calculates risk based on maternal and pregnancy details.
  5. Report Delivery: Results are usually available within 2–4 working days.

How to Interpret the Results?

The results are expressed as a risk ratio, not as positive or negative.

S. No.Result TypeMeaning
1Low RiskLow chances of chromosomal abnormality
2High RiskFurther diagnostic testing may be recommended

If report shows high chances of risk then doctor advice of doing these tests:

  • Detailed Level II Ultrasound
  • NIPT
  • Amniocentesis

What are the benefits of the Quadruple Marker Test?

  • Safe and quick
  • Simple blood test
  • No harm to the baby
  • Detect serious conditions early
  • Reassurance in most low-risk cases
  • Supports pregnancy decisions

What are the limitations of the Test?

While helpful, the Quadruple Marker Test has certain limitations:

  • Only screening test is not diagnostic.
  • False positives may occur.
  • Some cases may go undetected.
  • Accurate gestational age is necessary for correct interpretation.
  • Does not detect all genetic conditions.

What are the preparations before the Test?

No special preparation is required.

However, inform your doctor about:

  • Correct gestational age
  • Multiple pregnancies IVF conception
  • Diabetes or other medical conditions

Why Choose City Imaging and Clinical Labs?

When it comes to pregnancy screening, accuracy and trust are essential.

At City Imaging, we offer:

  • Advanced diagnostic equipment
  • Highly qualified laboratory professionals
  • Timely and precise reports
  • Affordable pricing
  • Clean and patient-friendly environment
  • Trusted diagnostic services in the city

How much does it cost to do a quadruple marker test price in Delhi?

The quadruple marker test can be performed in Delhi at a cost of around INR 2,000 INR 4,500. The cost can vary at different labs and locations and also depends on the diagnostic centre, whether you are doing it in a government or private diagnostic centre.

Which Quadruple marker test centre is near me in Delhi?

The Quadruple marker test centre near me in Delhi is City Imaging, which has world class medical equipment and renowned professionals which will listen to your each query carefully and provide better solutions to your medical problems. They do tests at affordable rates and give special discounts to needy ones.  This testing centre for marker tests is recognised by government institutions such as NABH and NABL and has long experience in diagnostic fields.

Final Words

The Quad Marker Test is available to be used to assess whether a fetus might be affected by certain types of chromosomal disorders and neural tube defects. It provides the ability to identify pregnancies that might be at increased risk for these disorders and to provide the parents the ability to make informed choices regarding their pregnancies; however, the test is not diagnostic but rather identifies pregnancies in need of additional investigation.

If your doctor recommends that you schedule an appointment for a Quad Marker Test, consider scheduling with City Imaging & Clinical Laboratories. We have world class technology and advanced machines with long experience in doing these tests with accuracy.

 

Frequently Asked Questions (FAQs)

 

Does the Quadruple Marker Test must be done during pregnancy?

No, it is not essential but doctors recommend this test during the second trimester.

How accurate is the quadruple marker test?

Its accuracy is almost 80% in down syndrome cases and in neural tube defects.

Can this test confirm Down syndrome?

No. It only calculates the risk of it but for confirmatory other tests are required.

When to do this test during pregnancy?

The quadruple test is done during 4 or 5 months of pregnancy.

Does the test harm the baby?

No. It is completely safe as it only involves maternal blood sampling.

Is quadruple marker safe?

Yes, it is a very safe and has little discomfort while doing this test.

When will I receive my report?

Reports are generally available within 24 to 48 hours.

Is the quadruple marker painful?

No, it causes only a little bit of pain during the collection of blood samples.

How long does the test take?

The procedure usually takes 20–30 minutes but also depends on your slot.

Is hospitalisation required?

No, you can go home the same day after testing.

Can quadruple markers confirm abnormality?

It is a screening test, for confirming abnormality in an unborn baby you should do other tests.

Is fasting required for this test?

No. Fasting is not required for this test but you may take consent from the doctor before doing this test.

Can I book an online quadruple marker test in Delhi?

Yes, you can book an online quadruple marker test in Delhi from City Imaging very comfortably.

Which lab is best for doing quadruple marker tests in Delhi?

City Imaging is best for doing quadruple marker tests in Delhi as it has advanced medical equipment and experienced professionals.

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