NIPT WITH MICRODELETIONS

NIPT (Non-Invasive Prenatal Testing) is an effective method of determining and examining genetic wellness of an unborn child. While classical NIPT tests only help to monitor some chromosomal disorders, NIPT with microdeletions screens further genetic information about the baby. NIPT with Microdeletions is recommended by many doctors to pregnant women especially those having a family history of genetic disorder or those who impregnate through assisted reproductive technologies. Our facility, City Imaging, will provide advanced NIPT (Twins) testing to allow you as parents to make early decisions about your pregnancy. It is estimated that the cost for this test can be somewhere around INR 22,000 to INR 29,000.

What are Microdeletions?

Microdeletions are small missing segments of chromosomes. Unlike larger chromosomal abnormalities, these deletions are tiny but can still lead to serious genetic conditions.

They are also known as:

• Sub chromosomal deletions
• Copy Number Variations

What is NIPT with Microdeletions?

Microdeletion NIPT is an all-encompassing NIPT. It not only detects genetic variations that are commercially available but also detects small pieces of deletion from the DNA (microdeletions).

The technique used in NIPT to examine DNA is based on sequencing technique. Examining DNA from mother and fetus at the same time helps detect chromosomal information from fetus and mother.

This is made possible by the latest sequencing technique, which allows NIPT to detect changes that can only be detected by the invasive approach.

Why is NIPT Important in Pregnancies?

It helps in early detection of conditions such as:

• Down Syndrome
• Edwards Syndrome
• Patau Syndrome

How Does NIPT with Microdeletions Work?

1. Blood Sample Collection
   A small blood sample is drawn from the mother.
2. DNA Extraction
   Cell-free fetal DNA is isolated from maternal blood.
3. Genetic Analysis
   Advanced sequencing identifies chromosomal abnormalities and microdeletions.
4. Report Generation
   Results are categorized as:
   • Low Risk
   • High Risk
   • Inconclusive

What Does NIPT with Microdeletions Detect?

Key conditions detected:

• Trisomy 21
• Trisomy 18
• Trisomy 13
• Sex chromosome abnormalities
• Fetal gender

What are the common Microdeletion Syndromes screened in NIPT?

What is the accuracy of NIPT in Pregnancies?

• Detection rate is around ­99% for Trisomy 21.

Accuracy is affected due to:

• Low fetal DNA fraction
• Vanishing twin syndrome
• Maternal health conditions

What are the benefits of NIPT with Microdeletions?

1. Safe
2. Early Detection
3. High Accuracy
4. Useful for High-Risk Pregnancies

• Advanced maternal age
• Family history of genetic disorders
• Pregnancy complications

What are the limitations of NIPT in Twin Pregnancies?

Its limitations are:

Not a diagnostic test

1. NIPT is a screening test. Positive results require confirmation through:

• Amniocentesis
• Chorionic Villus Sampling

2. Cannot identify which Twin is affected

3. Possible False Results

4. Limited Detection Scope

Who Should Consider NIPT with Microdeletions?

NIPT is recommended for:

• Women carrying twins
• Women above 35 years of age
•  Abnormal ultrasound findings
• Genetic disorder history
• IVF or assisted pregnancies

What is the preparation for the NIPT Test?

You should:

• Inform your doctor about medical history
• Share details of twin type
• Follow your doctor’s guidance

How to understand NIPT results?

Results are usually categorized as:

1. Low Risk (Negative)

• Indicates low probability of chromosomal abnormalities
• No further testing required in most cases

2. High Risk (Positive)

• Suggests increased likelihood of a condition
• Requires confirmatory diagnostic testing

3. No Call

• May occur due to low fetal DNA
• Repeat testing may be recommended

What is the difference between NIPT and Traditional Prenatal Tests?

Why Choose City Imaging for NIPT with Microdeletions?

We provide:

• Advanced genetic screening technology
• Accurate and reliable reports
• Experienced diagnostic specialists
• Quick turnaround time
• Patient-focused care

Which NIPT with Microdeletions test centre is near me?

The NIPT with Microdeletions test centre near me in Delhi is City Imaging, which gives quality tests at affordable rates and provides special discounts for poor people. This testing centre is accredited from Government institutions like NABL and NABH and centres have a vast expertise in the diagnostic field with highly experienced doctors.

How to book NIPT with Microdeletions test online at City Imaging?

You can book an NIPT with Microdeletions test at City Imaging by going to their website and book the test in no time. They also provide home collection booking and upload prescriptions on websites.

What is the price of a test in Delhi?

The NIPT with Microdeletions test can be performed in Delhi at the price ranges from INR 22,000 to INR 29,000. The cost can vary at different labs and locations and also depends on the diagnostic centre, whether you are doing it in a government or private diagnostic centre. For affordable and transparent pricing, contact City Imaging today.

Frequently Asked Questions (FAQs)

Is NIPT 100% accurate?

No, it is highly accurate but not diagnostic.

What to do if NIPT with Microdeletions test results come positive?

The patient has to do confirmatory tests like amniocentesis.

When will I get my report?

Most reports are available after 5 to10 days depending upon the staff availability and number of patients. 

How much time does the NIPT with the Microdeletions test take?

To do the NIPT with Microdeletions test, it takes a maximum of 10 minutes but also depends on your slot and staff availability.

Is NIPT with the Microdeletions test painful?

No, it is completely painless. You have to give a blood sample which causes little discomfort while collecting.

Do I need to fast before the test?

Fasting is not needed for doing NIPT with Microdeletions test. It has nothing to do with the NIPT test.

Can I go home immediately after NIPT with the Microdeletions test?

Yes, you can go home the same day and resume your normal activities unless advised to take rest.

Is NIPT with Microdeletions tests safe for unborn children?

Yes, the NIPT with Microdeletions test is safe for unborn children and for mothers also.

How often should NIPT with Microdeletions test be done?

It depends on the advice of the doctor and the patient's health. Mostly, it is done after 10 weeks of pregnancy.

Can NIPT with Microdeletions test detect cancer?

No. It does not confirm cancer tests, rather it monitors unborn babies.

Can I book an online NIPT with Microdeletions test in Delhi?

Yes, you can book an online NIPT with Microdeletions test in Delhi from City Imaging very comfortably.

Which lab is best for doing NIPT with Microdeletions test in Delhi?

City Imaging is best for doing NIPT with Microdeletions test in Delhi as it has advanced medical equipment and experienced professionals.