Overview

Pains in the back, stiffness in the joints and mysterious swelling can disrupt your way of living. The reason for these signs can be due to issues in your musculoskeletal system or in autoimmune disorder. One of the major diagnostic tests aimed at establishing whether an autoimmune disease is present is named HLA-B27 PCR test.

City Imaging provides accurate HLA-B27 PCR tests by employing advanced molecular diagnostic techniques. The specialists of the laboratory ensure precise test results to make proper early diagnosis of an autoimmune disease. The price of the HLA-B27 by PCR test varies from INR 1600 to INR 4000.

What is the HLA-B27 by PCR Test?

Pains in the back, stiffness in the joints and mysterious swelling can disrupt your way of living. The reason for these signs can be in some issues related to your musculoskeletal system or in autoimmune disorder. One of the major diagnostic tests aimed at establishing whether an autoimmune disease is present is named HLA-B27 PCR test.

Why is the HLA-B27 by PCR Test done?

Physicians suggest the test in cases when a patient has signs indicating the presence of autoimmune forms of arthritis or an inflammatory disease. The test has the following applications:

• Differentiating unexplained cases of chronic back pain
• Researching cases of inflammatory arthritis
• Identifying juvenile idiopathic arthritis
• Evaluating recurrent eye inflammation

What are the conditions associated with HLA-B27?

A positive HLA-B27 result is commonly associated with several conditions. These are:

• Psoriatic Arthritis
• Juvenile Idiopathic Arthritis
• Ankylosing Spondylitis
• Reactive Arthritis
• Acute Anterior Uveitis

What are the symptoms that may require HLA-B27 Testing?

Your doctor may recommend this test if you experience:

• Neck stiffness
• Pain in the hips
• Swollen joints
• Heel pain
• Persistent joint inflammation
• Reduced spinal flexibility
• Eye redness
• Blurred vision
• Recurrent episodes of uveitis

What is PCR Technology?

PCR, or Polymerase Chain Reaction, is a cutting-edge laboratory practice which enfolds the amplification of minimal quantities of DNA, making it easier to find specific genes with outstanding accuracy.

When compared to older methods of testing, PCR provides:

• High sensitivity
• High specificity
• Faster results
• Better accuracy
• Reliable genetic detection
• Reduced chances of false results

How to prepare for the HLA-B27 by PCR Test?

The HLA-B27 by PCR test usually requires minimal preparation.

Generally:

• Fasting is not required.
• Continue taking medications unless advised otherwise.
• Drink plenty of water.
• Inform your doctor about any ongoing treatments.
• Carry previous medical reports if available.

What is the HLA-B27 by PCR Test procedure?

In reality, the whole blood draw procedure is pretty straightforward and lasts only for a couple of minutes.

Step 1

You take a comfortable seat in the collection area.

Step 2

The healthcare provider disinfects the area with an antiseptic agent.

Step 3

A specialised syringe is inserted into a vein of the patient’s arm.

Step 4

A tiny blood sample gets into a special tube to hold it after the needle is removed and pressure is applied to stop the bleeding.

The blood sample is then sent to the molecular laboratory for DNA extraction and analysis using the PCR technique.

Is the Test painful?

The test involves only a routine blood sample.

Most people experience:

• Mild discomfort
• A brief needle prick
• Slight bruising
• Temporary soreness

How to understand the Test results?

The HLA-B27 by PCR test generally reports one of two outcomes.

Positive Result

The presence of HLA-B27 is indicated by a positive outcome.

This suggests greater genetic predisposition regarding autoimmune diseases. Nevertheless, it should be noted that there are many healthy carriers of HLA-B27 who have never been sick.

Additional testing is necessary, including:

• Clinical examination
• Medical history
• MRI or X-ray imaging
• ESR and CRP tests
• Rheumatology consultation

Negative Result

A negative result indicates that the HLA-B27 gene was not present.

What are the advantages of PCR-Based HLA-B27 Testing?

PCR technology provides several advantages over conventional methods.

These include:

• Highly accurate detection
• Direct DNA analysis
• Excellent sensitivity
• Excellent specificity
• Reliable results
• Faster reporting
• Lower risk of laboratory error
• Suitable for clinical diagnosis

What are the benefits of the HLA-B27 by PCR Test?

The test offers several important benefits.

• Early Diagnosis
• Better Treatment Planning
• Improved Disease Monitoring
• Supports Imaging Findings
• Family Risk Assessment

What other Tests may be recommended?

Depending on your symptoms, your doctor may also recommend:

• Erythrocyte Sedimentation Rate
• C-Reactive Protein
• Rheumatoid Factor
• Anti-CCP Antibody
• ANA Profile
• MRI Spine
• MRI Sacroiliac Joints
• X-ray Pelvis
• Complete Blood Count

Are there any risks associated with HLA-B27 by PCR Test?

The HLA-B27 by PCR test is considered very safe.

Minor risks include:

• Temporary pain
• Mild bruising
• Slight bleeding
• Rare infection at the needle site

Why choose City Imaging for HLA-B27 by PCR Testing?

Our advantages include:

• Advanced PCR laboratory technology
• Highly experienced laboratory professionals
• Accurate and reliable reports
• Strict quality control standards
• Hygienic sample collection
• Timely report delivery
• Affordable pricing
• Comprehensive diagnostic services under one roof
• Friendly and patient-focused staff

What is the price of the HLA-B27 BY PCR test in Delhi?

The HLA-B27 BY PCR test can be performed in Delhi for a price ranging from INR 1600 to INR 4000. The price may vary slightly depending on the machine used, location and type of test.

When should you consult a doctor?

Consult your healthcare provider if you experience:

• Persistent back pain before the age of 45
• Morning stiffness that improves with activity
• Swollen joints
• Recurrent eye inflammation
• Pain in the hips or buttocks
• Chronic joint pain without injury
• Family history of ankylosing spondylitis or related disorders

How to book HLA-B27 BY PCR test online at City Imaging?

A patient can schedule their HLA-B27 BY PCR test on City Imaging's website or by calling them for assistance in making an appointment. The technician also visits your house to collect samples by booking a home collection at the website. Also reports are also transferred to patients in soft copy so visiting lab centres is not necessary.

Which HLA-B27 BY PCR test centre is near me?

Delhi-based City Imaging has state-of-the-art medical equipment that enables precise testing. Here, well-trained employees compassionately and carefully respond to your enquiries. City Imaging provides an outstanding environment and has well equipped labs with modern machines.

Frequently Asked Questions (FAQs)

Is HLA-B27 hereditary?

Yes, but not everyone with the gene suffers from the disease.

Will I be required to fast prior to the HLA-B27 PCR test?

Generally, you won’t be required to fast unless your doctor has advised you to do so for another procedure.

Is HLA-B27 an indicator of ankylosing spondylitis?

No, just the presence of HLA-B27 doesn’t tell you if a person has ankylosing spondylitis or not.

Does HLA-B27 testing have any other name?

The HLA-B27 test is known as HLA B – 27.

When do you get the results of the HLA-B27 test?

Most labs will tell you their results in a few working days; however, the whole process is time-consuming.