BETA 2 GLYCOPROTEIN I (GP1) IgM

1000

Additional information
DepartmentSEROLOGY
Speciality NameBETA 2 GLYCOPROTEIN I (GP1) IgM
Test typePathology
Also known asB2 glycoprotein IgM, B2 IgM, BETA 2 GP1 IgM
Report24 Hours
AvailabilityAll centre

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Preparation

No Patient preparation needed.

Overview

The Beta-2 Glycoprotein 1 (GP1) IgM test is a popular test that is done to check autoimmune disease and blood clot disorder such as Antiphospholipid Syndrome. It is an affordable test that is simple and gives results quickly. The accuracy of this test is very high and is suggested to patients who have blood clot disorder symptoms. Normally, the cost of the test ranges from INR 700 to INR 1300.

What is Beta-2 Glycoprotein 1 (GP1)?

Beta-2 Glycoprotein 1 (β2GP1) is a protein which is present in the blood of human beings. This protein has the ability to bind with phospholipids, which are fat particles found in cell membranes. This is how the body controls the formation of clots.

Antibodies to β2GP1 are made by the immune system mistakenly.

These antibodies are called:

  • Anti-Beta-2 Glycoprotein 1 antibodies
  • IgM type is one of the main classes tested

What is the Beta-2 GP1 IgM Test?

The Beta-2 GP1 IgM test is a blood test that determines IgM antibodies directed against Beta-2 Glycoprotein 1.

Key Points:

  • Detects autoimmune activity
  • Diagnose Antiphospholipid Syndrome
  • Checks risk of clot formation
  • Often done along with other tests like:
    • Anticardiolipin antibodies
    • Lupus anticoagulant

Why is the Beta-2 GP1 IgM Test Done?

It is done to check:

1. Antiphospholipid Syndrome

2. Recurrent Blood Clots

  • Deep vein thrombosis
  • Pulmonary embolism
  • Stroke at a young age

3. Pregnancy Complications

  • Recurrent miscarriages
  • Stillbirth
  • Preterm delivery

4. Autoimmune Disorders

  • Lupus erythematosus

5. Clotting Disorders

Which symptoms may require this Test?

You may need this test if you experience:

  • Swelling in legs
  • pain in legs
  • Shortness of breath
  • Repeated pregnancy loss
  • Frequent headaches
  • Neurological issues
  • Blood clotting episodes

What is the preparation for the Test?

Before the Test:

  • No fasting needed
  • Continue regular diet
  • Inform your doctor about medications

Sample Type:

  • Blood sample

What is the procedure of B2 glycoprotein IgM?

In this test, the first medical health care person collects the blood by injecting a needle into the vein of the arm and collects the small amount of blood in a designated test tube for examining specific IgM antibodies. ELISA technique is used to detect antibodies. The reports are collected within the same day or other day depending on the lab and on your slot.

What is the normal range of Beta-2 GP1 IgM Test?

S. No.Result (SMU Units)Interpretation
1< 15.0 SMUNegative
215.0 – 39.9 SMUWeak Positive
340.0 – 79.9 SMUPositive
4≥ 80.0 SMUStrong Positive

SMU = Standard IgM Units

How to understand the results?

1. Negative Result

  • No significant antibodies detected
  • Low risk of APS

2. Weak Positive

  • May indicate early or mild autoimmune activity
  • Requires follow-up testing

3. Positive Result

  • Suggests increased risk of clotting disorders
  • Needs correlation with clinical symptoms

4. Strong Positive

  • High likelihood of Antiphospholipid Syndrome
  • Requires immediate medical attention

Which tests are combined with B2 IgM?

The Beta-2 GP1 IgM test should not be used alone for diagnosis.

Doctors usually combine it with:

  • Anticardiolipin antibody test
  • Lupus anticoagulant test

What is the clinical significance of B2 glycoprotein IgM?

It is linked to:

1. Blood Clot Formation

These antibodies can increase the tendency of blood to clot in:

  • Veins
  • Arteries

2. Pregnancy Risks

  • Miscarriages
  • Placental complications

3. Autoimmune Disorders

Common in patients with lupus and similar conditions

What are the advantages of doing the Test at City Imaging?

It offers:

  • Advanced diagnostic technology
  • Accurate ELISA-based testing
  • Experienced lab professionals
  • Quick and reliable reports
  • Affordable pricing

What are the limitations of the Test?

  • Cannot diagnose APS alone
  • Temporary antibody elevation may occur due to infections
  • Requires repeat testing for confirmation
  • Must be interpreted along with clinical findings

When Should You Consult a Doctor?

If:

  • Result is positive
  • History of blood clots
  • Planning pregnancy
  • Autoimmune disease symptoms

How to book B2 glycoprotein IgM test online at City Imaging?

Patients can book the B2 glycoprotein IgM test online at city imaging by visiting the website and book the appointment online. Patients can also dial numbers and they will guide you for booking a test. City imaging also provides a home sample collection feature through which professionals take samples of patients from their home and they don’t have to visit diagnostic centres.

What is the price of B2 glycoprotein IgM test in Delhi?

The B2 IgM test can be performed in Delhi at the price ranges from INR 700 to INR 1300. The price may vary slightly depending on the machine used, location and type of test.

Which B2 glycoprotein IgM test centre is near me in Delhi?

The B2 glycoprotein IgM test centre near me in Delhi is City Imaging which has a patient friendly environment, skilled radiology specialists, accurate and fast reports, modern equipment and convenient location. They provide tests at reasonable rates without compromising the quality of tests. This diagnostic centre is licensed and has long experience in diagnostic fields.

 

Frequently Asked Questions (FAQs)

 

What is the other name of Beta-2 Glycoprotein 1 (GP1) IgM?

It is also called as B2 glycoprotein IgM.

Is B2 glycoprotein IgM test compulsory during pregnancy?

It is not an essential test but doctors may recommend this test if symptoms may appear.

Is the B2 glycoprotein IgM test painful?

No, it involves a routine conventional blood collection from a vein which may cause little discomfort.

Is hospitalization required?

No, you can go home the same day after testing as it is similar to other blood tests.

Can B2 glycoprotein IgM confirm abnormality?

It is a screening test to check any threat of blood clotting, for confirming abnormality in an unborn baby you should do other tests.

Can I book an online B2 glycoprotein IgM test in Delhi?

Yes, you can book an online B2 glycoprotein IgM test in Delhi from City Imaging very comfortably.

Which lab gives test reports with accurate results in Delhi?

City Imaging has a track record in giving the reports with high accuracy because it has advanced medical equipment and experienced professionals.

Is the B2 IgM test done prior to pregnancy?

Yes, doctors advised to do B2 glycoprotein IgM test for confirm immunity of pregnant women and aids to avoid pregnancy complications.

Do I need fasting for doing B2 glycoprotein IgM test?

No fasting is not needed for doing B2 glycoprotein IgM test but you must also take consent from the doctor.

What to do if my B2 glycoprotein IgM reports come negative?

There is no need to worry but you must take great care and do regular checkups if symptoms appear again.

Is the test safe if done during pregnancy?

Yes, it is completely safe. It is the same routine blood test where a blood sample is taken from the vein of the arm.

How soon will I get my results?

Most reports in many labs are available within 24 hours but it also depends on your slot.

Can B2 glycoprotein IgM test be done anytime during pregnancy?

Yes, it can be done in any month of pregnancy but doctors recommend it in early pregnancy.

What if B2 glycoprotein IgM is positive?

It usually indicates blood clot disorder. If the result shows more positive then it indicates Antiphospholipid Syndrome.

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